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KMID : 0043320070300070799
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Archives of Pharmacal Research
2007 Volume.30 No. 7 p.799 ~ p.802
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Two New Coumarin Glucosides from the Roots of Angelica apaensis and Their Anti-Platelet Aggregation Activity
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Xiao Wei Lie
Li Sheng-Hong
Shen Yun-Heng
Niu Xue-Mei
Sun Han Dong
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Abstract
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Two new coumarin glucosides, 11-O-β-D-glucopyranosyl thamnosmonin (1) and 12-O-β-D-glucopyranosyl gosferol (2), were isolated from the roots of Angelica apaensis. Their structures were elucidated spectroscopically. Both compounds showed weak inhibitory effects on rabbit platelet aggregation induced by PAF, AA and APD.
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KEYWORD
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Anti-platelet aggregation, 11-O-β-D-glucopyranosyl thamnosmonin, 12-O-β-D-glucopyranosyl gosferol, Coumarin, Angelica apaensis, Umbelliferae
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